Ultrasound Database •
The target strength is a measure of the percentage of the acoustic energy hitting the target that is reflected back to the transducer.
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Targeted ultrasound contrast agents provide advantages compared with usual microbubble blood pool agents. The goal of targeted ultrasound contrast agents is to significantly and selectively enhance the detection of a targeted vascular site. Tissue-specific ultrasound contrast agents improve the image contrast resolution through differential uptake. Targeted drug delivery via contrast microbubbles is another contrast media concept and provides the potential for earlier detection and characterization of disease. Targeted contrast imaging provides a higher sensitivity and specificity than obtained with a nontargeted contrast agent. The detection of disease-indicative molecular signatures may allow early assessment of pathology on a molecular level. Molecular imaging should be an efficient and less invasive technique to obtain three-dimensional localization of pathology. Ultrasound agents typically remain within the vascular space, and therefore possible targets include molecular markers on thrombus, endothelial cells, and leukocytes. Targeted contrast agents permit noninvasive detection of thrombus, cancer, inflammation, or other sites where specific integrins or other adhesion molecules are expressed. Adhesion molecules such as monoclonal antibodies, peptides, asialoglycoproteins, or polysaccharides are incorporated into the shell of the microbubble or liposome. After injection into the bloodstream, the targeted agent accumulates via adhesion receptors at the affected site, enhancing detection with an ultrasound system. See also Acoustically Active Lipospheres, and Tissue-Specific Ultrasound Contrast Agent. • View NEWS results for 'Targeted Contrast Imaging' (1). Further Reading: News & More:
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From ESAOTE S.p.A.; 'With Technos MP version, Technos Family has been acknowledged for its high level of ergonomics, avant-garde technology system, constant accuracy and good performance-price ratio.' •
From ESAOTE S.p.A.; 'Technos MPX is an incredibly powerful, multi-modality ultrasound system. Its advanced diagnostic capabilities allow physicians and sonographers to make more confident diagnoses, faster and easier. As a result, Technos MPX improves workflow and increases patient throughput.' Specifications for this system will be available soon. •
From ESAOTE S.p.A.; 'With Technos Partner version, Technos Family has been recognized as a very adaptable systems group both from a technological and an ergonomic point of view.' |