The M-mode (Motion-mode) ultrasound is used for analyzing moving body parts (also called time-motion or TM-mode) commonly in cardiac and fetal cardiac imaging. The application of B-mode and a strip chart recorder allows visualization of the structures as a function of depth and time. The M-mode ultrasound transducer beam is stationary while the echoes from a moving reflector are received at varying times.
A single beam in an ultrasound scan is used to produce the one-dimensional M-mode picture, where movement of a structure such as a heart valve can be depicted in a wave-like manner. The high sampling frequency (up to 1000 pulses per second) is useful in assessing rates and motion, particularly in cardiac structures such as the various valves and the chamber walls.

M-mode (Motion-mode) ultrasound shows the motion of cardiac structures. M-mode echocardiography records the amplitude and rate of motion of a moving structure in real time by repeatedly measuring the distance of the object from the single transducer at a given moment. The single sound beam is transmitted and reflected signals are displayed as dots of varying intensities, creating lines across the screen. It yields a one-dimensional image, sometimes called an 'ice pick' view of the heart.
M-mode echocardiography is used to detect valvulopathies (calcifications, etc.) and cardiomyopathies (dyskinesis, aneurysm, etc.).

See also Bicycle Stress Echocardiography, Transthoracic Echocardiography, and Transesophageal Echocardiography.

From POINT Biomedical Corp
M1091 is a nitrogen-filled submicron ultrasound contrast agent with a bilayered shell composed of a biodegradable polymer and a human serum albumin outer coating. This agent under development consists of microbubbles that have a peak volumetric diameter of 0.57 μm, and a mean initial diameter of 800 nm, with more than 93% having a diameter smaller than 1 μm. Manipulations in the manufacturing process can generate structures varying in size and wall thickness.
M1091 and M1134 are two agents made of the same polymer with the same relative wall thickness, differing only in the microbubble diameter.

From POINT Biomedical Corp
M1134 is a nitrogen-filled submicron ultrasound contrast agent under development with a bilayered shell composed of a biodegradable polymer and a human serum albumin outer coating. The microbubbles have initial diameters from 500 nm to 1.3 μm, with more than 50% having a diameter smaller than a micron.
M1134 can be used in targeted contrast imaging by entering the lymphatic system after injection into the interstitium and accumulation at lymph nodes.
M1134 and M1091 are two agents made of the same polymer with the same relative wall thickness, differing only in the microbubble diameter.

(MRgFUS) Magnetic resonance guided focused ultrasound is a surgical procedure that uses high intensity focused ultrasound waves to destroy tissue in combination with magnetic resonance imaging (MRI), which guides the treatment.
With focused ultrasound waves uterine fibroids are heated and destroyed (ablated) inside the MRI device , allowing the physician to plan, monitor and control the treatment with temperature sensitive images while it is in progress.

See also High Intensity Focused Ultrasound, and Interventional Ultrasound.