Peripheral veins are easily tested using a 5 to 10 MHz transducer. The venous walls are smooth, thin, and compressible. Venous ultrasound imaging requires the compression of the veins in the transverse view. If compression is performed in the longitudinal view, the vein may roll away from the transducer possibly creating a false-negative examination.
The lumen of the normal vein is echo free. Increasing the gain will display low level echoes representing venous blood moving towards the heart. When performing Doppler spectral analysis or color Doppler the gate should be placed in the center of the vessel. In case of a non-obstructing or recanalized thrombosis, the Doppler gate should be placed within the remaining vessel lumen for flow detection.

See also Maximum Venous Outflow and Zero Offset.