(PII) Pulse inversion imaging (also called phase inversion imaging) is a non-linear imaging method specifically made for enhanced detection of microbubble ultrasound contrast agents. In PII, two pulses are sent in rapid succession into the tissue; the second pulse is a mirror image of the first. The resulting echoes are added at reception. Linear scattering of the two pulses will give two echoes which are inverted copies of each other, and these echoes will therefore cancel out when added.
Linear scattering dominates in tissues. Echoes from linear scatterers such as tissue cancel, whereas those from gas microbubbles do not. Non-linear scattering of the two pulses will give two echoes which do not cancel out completely due to different bubble response to positive and negative pressures of equal magnitude. The harmonic components add, and the signal intensity difference between non-linear and linear scatterers is therefore increased. The resulting images show high sensitivity to bubbles at the resolution of a conventional image.
In harmonic imaging, the frequency range of the transmitted pulse and the received signal should not overlap, but this restriction is less in pulse inversion imaging since the transmit frequencies are not filtered out, but rather subtracted. Broader transmit and receive bandwidths are therefore allowed, giving shorter pulses and improved axial resolution, hence the alternative term wideband harmonic imaging. Many ultrasound machines offer some form of pulse inversion imaging.

See also Pulse Inversion Doppler, Narrow Bandwidth, Dead Zone, Ultrasound Phantom.

A logarithmic measure of sound loudness closely related to the decibel. The unit decibel is used for objective measurements, that means, they measure the actual pressure of the sound waves as recorded using a microphone. The unit phon is used for subjective measurements, which means, measurements made using the ears of a human listener.
A sound has the loudness 'p' phon if it seems to the listener to be equal in loudness to the sound of a pure tone of the frequency 1 kilohertz and strength 'p' decibel. A measurement in phons will be similar to a measurement in decibel, but not identical, since the perceived loudness of a sound depends on the distribution of frequencies in the sound as well as the pressure of the sound waves. In the U.S., sound loudness is frequently measured in sones rather than phons: a sound of loudness x sones has loudness 10 log2 x + 40 phons.

See also Acoustic Noise.

A piezoelectric ceramic is made of crystalline substance which creates charges of electricity by the application of pressure and vice versa. This material is used in ultrasound transducers to create the sound waves.

See also Composite Array.

A piezoelectric crystal changes the physical dimensions when subjected to an electric field. When deformed by external pressure, an electric field is created across the crystal. Piezoelectric ceramic and crystals are used in ultrasound transducers to transmit and receive ultrasound waves.
The piezoelectric crystal in ultrasound transducers has electrodes attached to its front and back for the application and detection of electrical charges. The crystal consists of numerous dipoles, and in the normal state, the individual dipoles have an oblique orientation with no net surface charge.
In ultrasound physics, an electric field applied across the crystal will realign the dipoles and results in compression or expansion of the crystal, depending on the direction of the electric field. For the transmission of a short ultrasound pulse, a voltage spike of very short duration is applied, causing the crystal to initially contract and then vibrate for a short time with its resonant frequency.

See also Composite Array, Transducer Pulse Control, and Temporal Peak Intensity.

A transducer is a device, usually electrical or electronic, that converts one type of energy to another. Most transducers are either sensors or actuators. A transducer (also called probe) is a main part of the ultrasound machine. The transducer sends ultrasound waves into the body and receives the echoes produced by the waves when it is placed on or over the body part being imaged.
Ultrasound transducers are made from crystals with piezoelectric properties. This material vibrates at a resonant frequency, when an alternating electric current is applied. The vibration is transmitted into the tissue in short bursts. The speed of transmission within most soft tissues is 1540 m/s, producing a transit time of 6.5 ms/cm. Because the velocity of ultrasound waves is constant, the time taken for the wave to return to the transducer can be used to determine the depth of the object causing the reflection.
The waves will be reflected when they encounter a boundary between two tissues of different density (e.g. soft tissue and bone) and return to the transducer. Conversely, the crystals emit electrical currents when sound or pressure waves hit them (piezoelectric effect). The same crystals can be used to send and receive sound waves; the probe then acts as a receiver, converting mechanical energy back into an electric signal which is used to display an image. A sound absorbing substance eliminates back reflections from the probe itself, and an acoustic lens focuses the emitted sound waves. Then, the received signal gets processed by software to an image which is displayed at a monitor.
Transducer heads may contain one or more crystal elements. In multi-element probes, each crystal has its own circuit. The advantage is that the ultrasound beam can be controlled by changing the timing in which each element gets pulsed. Especially for cardiac ultrasound it is important to steer the beam.
Usually, several different transducer types are available to select the appropriate one for optimal imaging. Probes are formed in many shapes and sizes. The shape of the probe determines its field of view.
Transducers are described in megahertz (MHz) indicating their sound wave frequency. The frequency of emitted sound waves determines how deep the sound beam penetrates and the resolution of the image. Most transducers are only able to emit one frequency because the piezoelectric ceramic or crystals within it have a certain inherent frequency, but multi-frequency probes are also available.
See also Blanking Distance, Damping, Maximum Response Axis, Omnidirectional, and Huygens Principle.