Retrolenticular afterglow could occur through diffraction and refraction on interfaces. A circular object may act as a lens to the ultrasound beam, showing an artifact region of increased echogenicity.

The acoustic lens is placed at the time the transducer is manufactured and cannot be changed. The acoustic lens is generally focused in the mid field rather than the near or far fields. The exact focal length varies with transducer frequency, but is generally in the range of 4-6 cm for a 5 MHz curved linear probe and 7-9 cm for a 3.5 MHz curved transducer.
Placing the elevation plane (z-plane) focal zone of the acoustic lens in the very near or far field would improve the beam width at precisely those depths. However, this would degrade the beam width to a much greater and unacceptable degree at all other depths.
There are some chemicals in ultrasound couplants that can degrade the acoustic lens, destroy bonding, or change the acoustic properties of the lens. Problematic chemicals include mineral oil, silicone oil, alcohol, surfactants, and fragrances. Fragrance can affect the transducer's acoustic lens or face material by absorption over time into elastomer and plastic materials, thus changing the material's weight, size, density, and acoustic impedance. Surfactants can degrade the bond between the lens and the piezoelectric elements and contribute to the accelerated degeneration of the lens.

See also Retrolenticular Afterglow.

Echogenicity is the ability of a medium to create an echo, for example to return a signal when tissue is in the path of the sound beam. The ultrasound echogenicity is dependent on characteristics of tissues or contrast agents and is measured by calculating the backscattering and transmission coefficients as a function of frequency.
The fundamental parameters that determine echogenicity are density and compressibility. Blood is two to three orders of magnitude less echogenic than tissue due to the relatively small impedance differences between red blood cells and plasma. The tissue echogenicity can be increased by ultrasound contrast agents. Encapsulated microbubbles are highly echogenic due to differences in their compressibility and density, compared to tissue or plasma.
Microbubbles are 10,000 times more compressible than red blood cells. The compressibility of air is 7.65 x 10−6 m2/N, in comparison with 4.5 x 10-11 m2/N for water (on the same order of magnitude as tissue and plasma). This impedance mismatch results in a very high echogenicity. An echo from an individual contrast agent can be detected by a clinical ultrasound system sensitive to a volume on the order of 0.004 pl.

See also Isoechogenic, Retrolenticular Afterglow, and Sonographic Features.