Microbubbles filled with air or inert gases are used as contrast agents in ultrasound imaging. Compression and rarefaction created by an ultrasound wave insonating a gas-filled microbubble along with the mechanical index of the ultrasonic beam lead to volume pulsations of the bubbles, and it is this change that results in the signal enhancement.
Microbubbles have diameters from 1 μm to 10 μm and a thin flexible or rigid shell composed of albumin, lipid, or polymer confining a gas such as nitrogen, or a perfluorocarbon. These microbubbles can cross the pulmonary capillaries and have a serum half-life of a few minutes. Microbubbles in the 1-10 μm range have their resonance at the frequencies used in diagnostic ultrasound (1−15MHz). Smaller bubbles resonate at higher frequencies. Caused by this coincidence, they are such effective reflectors.
The intrinsic compressibility of microbubbles is approximately 17,000 times more than water, and they are very strong scatterers of ultrasound. Under acoustic pressure the vibrating bubble radius may have a conventional linear response or a harmonic non-linear response. Microbubbles usually increase the Doppler signal amplitude by up to 30 dB.

The mirror artifact is similar to the reverberation artifact. Mirror image artifacts (mirroring) can occur if the acoustical impedances of the tissue is too much different and the ultrasound is reflected multiple times on tissue layers. The echo detected does not come from the shortest sound path, the sound is reflected off an angle to another interface so that like a real mirror, the artifact shows up as the virtual object.
An empyema or lung abscess can be simulated by a mirror image artifact of a hepatic cyst. This liver lesion can appear like a lesion within the lung because the wave is reflected off the diaphragm back into the liver. The angle of reflection is equal to the angle of incidence. The sound pulse hits the interfaces within the liver lesion and is reflected back to the diaphragm once again with an angle of reflection equal to the angle of incidence and then back to the transducer.
Also by a pelvic ultrasound scan the sound can be reflected off the rectal air at an angle so that the deep wall of an artifactual cyst represents the mirror image of the inferior and anterior walls of the bladder. Mirror image artifacts can cause other strange appearances such as invasion of a transitional cell carcinoma through the bladder wall.
Also called Cross Talk.

Molecular Biosystems, Inc. (MBI), founded in 1980, is a biomedical company developing a range of contrast agents for use with diagnostic ultrasound, magnetic resonance imaging (MRI), and computed tomography (CT).
Alliance Pharmaceutical Corp. acquires Molecular Biosystems in Nov. 2000.

From ESAOTE S.p.A.;
'The MyLab™30CV ultrasound system is an evolutionary step in ultrasound technology. Weighing less than 20 pounds, it is the first compact ultrasound system to deliver premium console performance. And with mobile, portable or stationary configurations, MyLab30CV can adapt to any clinical environment.'

(Osm) A unit of osmotic pressure used in physical chemistry, cell biology, and medicine.
Definition: 1 osmole is the osmotic pressure of a one molar solution (that is, a solution with a concentration of one mole per liter of solvent) of a substance that does not dissociate.
If chemical solutions are separated by a semipermeable membrane (a membrane that resists the passage of dissolved substances but permits the passage of the solvent, usually water), then the solvent will diffuse across the membrane to equalize the concentrations. This process is called osmosis.
Solutions with higher concentrations of dissolved substances are said to have higher osmotic pressure than solutions having lower concentrations; thus the solvent moves from an area of low osmotic pressure to an area of higher osmotic pressure.
Osmotic pressure depends on the total number of dissolved particles, so for a substance that dissociates into two ions, such as ordinary salt (sodium chloride), a one molar solution has an osmotic pressure of 2 osmoles. In practice, most measurements are in milliosmoles (mOsm). Typical values range from 20 mOsm for fresh water through 290 mOsm for typical human blood plasma to 1010 mOsm for salt water from the open ocean.

See also Part Per Million, and Mole.