Medical Ultrasound Imaging
Wednesday, 4 December 2024
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From GE Healthcare;; Optison is the first 'second generation USCA' marketed in the US. Ultrasound contrast agents used during an ultrasound imaging procedure, enable more accurate diagnosis of the patient's heart condition. The application of Optison allows to image the endocardial borders of the heart, to see cardiac wall motion abnormalities and to guide the selection and monitoring of treatment. Optison represents a class of microbubbles with a shell formed by sonicating a solution of capsules filled with a perfluoropropane gas. The high molecular weight slows microbubble dissolution and prolongs the enhancement for several minutes. The human albumin-stabilized cavitation bubbles have a surface tension of 0.9 N/m and a surface dilatational viscosity 0.08 msP. 'August 06, 2001 Molecular Biosystems Inc., a subsidiary of Alliance Pharmaceutical Corp, announced the amendment of the Optison Product Rights Agreement (OPRA) dated May 9, 2000 with Mallinckrodt Inc, a unit of Tyco Healthcare. Optison, an intravenous ultrasound contrast agent, was developed by MBI and is being marketed by Mallinckrodt in the U.S. and Europe. Under the amended agreement, MBI will receive an immediate cash payment plus additional unspecified royalties for a two-year period. The amendment of OPRA coincides with an announcement by Nycomed Amersham Imaging that Nycomed and Mallinckrodt will terminate their joint commercialization and development agreement for ultrasound contrast agents, including Optison, effective Dec. 31, 2001. Effective Jan. 1, 2002, all selling and marketing activities will be resumed solely by Nycomed Amersham.'
Drug Information and Specification
RESEARCH NAME
FS069
DEVELOPER
INDICATION -
DEVELOPMENT STAGE LVO -
For sale APPLICATION
intravenous/oral
TYPE
AlbuminN-acetyltryptophan,Caprylic acid
CHARGE
Slight Negative
Octafluoropropane
MICROBUBBLE SIZE
93% < 10μm
PRESENTATION
Five 3ml vials
STORAGE
Refrigerate 2-8 °C
PREPARATION
Hand agitate
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
DISTRIBUTOR
USA, EU
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[last update: 2023-11-06 01:42:00]