From POINT Biomedical Corp
M1091 is a nitrogen-filled submicron ultrasound contrast agent with a bilayered shell composed of a biodegradable polymer and a human serum albumin outer coating. This agent under development consists of microbubbles that have a peak volumetric diameter of 0.57 μm, and a mean initial diameter of 800 nm, with more than 93% having a diameter smaller than 1 μm. Manipulations in the manufacturing process can generate structures varying in size and wall thickness.
M1091 and M1134 are two agents made of the same polymer with the same relative wall thickness, differing only in the microbubble diameter.

From POINT Biomedical Corp
M1134 is a nitrogen-filled submicron ultrasound contrast agent under development with a bilayered shell composed of a biodegradable polymer and a human serum albumin outer coating. The microbubbles have initial diameters from 500 nm to 1.3 μm, with more than 50% having a diameter smaller than a micron.
M1134 can be used in targeted contrast imaging by entering the lymphatic system after injection into the interstitium and accumulation at lymph nodes.
M1134 and M1091 are two agents made of the same polymer with the same relative wall thickness, differing only in the microbubble diameter.

(MCE) Myocardial contrast echocardiography is a contrast enhanced ultrasound method that utilizes intravenous injected microbubbles as red blood cell tracers. MCE can assess myocardial perfusion both at rest and stress to evaluate viable myocardium after acute infarction.
MCE perfusion imaging improves the blood echoes during the microbubble passage and the imaging system suppresses the clutter represented by non-contrast-bearing tissue.

See also Injection Rate, Stress Echocardiogram, and Myomap.

Myomap is an investigational ultrasound contrast agent for assessment of myocardial perfusion and has been tested in animals to determine infarct volumes in cases of coronary artery occlusion. The deposit microbubbles of Myomap consist of air filled human serum albumin microcapsule with a thick and rigid shell.

Oscillation is a rhythmic periodic motion. Microbubbles, for example oscillate at their natural frequency at which they resonate most strongly.