A liver sonography is a diagnostic tool to image the liver and adjoining upper abdominal organs such as the gallbladder, spleen, and pancreas. Deeper structures such as liver and pancreas are imaged at a lower frequency 1-6 MHz with lower axial and lateral resolution but greater penetration. The diagnostic capabilities in this area can be limited by gas in the bowel scattering the sound waves.
The application of microbubbles may be useful for detection of liver lesions and for lesion characterization. Some microbubbles have a liver-specific post vascular phase where they appear to be taken up by the reticuloendothelial system (RES). Dynamic contrast enhanced scans in a similar way as with CT or MRI can be used to studying the arterial, venous and tissue phase.
After a bolus injection, early vascular enhancement is seen at around 30sec in arterialized lesions (e.g., hepatocellular carcinomas (HCC), focal nodular hyperplasia (FNH)). Later enhancement is typical of hemangiomas with gradually filling towards the center. In the late phase at around 90sec, HCCs appear as defects against the liver background. Most metastases are relatively hypovascular and so do not show much enhancement and are seen as signal voids in the different phases.
Either with an intermittent imaging technique or by continuous scanning in a nondestructive, low power mode, characteristic time patterns can be used to differentiate lesions.

See also Medical Imaging, B-Mode, High Intensity Focused Ultrasound, Ultrasound Safety and Contrast Medium.

The prostate is a walnut-shaped gland surrounding the beginning of the urethra in front of the rectum and below the bladder. The prostate can become enlarged (particularly in men over age 50) and develop diseases like prostate cancer or inflammation (prostatitis). A large tumor can be felt by a rectal examination. The most effective way of detecting the early signs of prostate cancer is a combination of a prostate-specific antigen (PSA) blood test and a prostate ultrasound examination.
An abnormally high level of PSA can indicate prostate cancer or other prostate diseases such as benign prostatic hypertrophy or prostatitis. The transrectal sonography is an important diagnostic ultrasound procedure in determining whether there is any benign enlargement of the prostate or any abnormal nodules.
The imaging is performed with a rectal probe, yielding high resolution. High resolution 3D ultrasound provides reliable and accurate determination of the size and the location of cancer. Additionally, ultrasound elastography is a technique in development to improve the specificity and sensitivity of cancer detection. Ultrasound is also used to detect whether cancerous tissue is still only within the prostate or whether it has begun to spread out and to guide a diagnostic biopsy or ultrasound therapy.

See also Brachytherapy, and High Intensity Focused Ultrasound.

Microwave thermotherapy is a type of ultrasound treatment in which body tissue is exposed to high temperatures. Focused ultrasound waves with high intensity damage and kill cancer cells or to make cancer cells more sensitive to the effects of radiation and certain anticancer drugs.
Examples for such treatments are the transurethral microwave thermotherapy (TUMT) and transurethral needle ablation (TUNA) that are used for benign prostatic hyperplasia.

See also High Intensity Focused Ultrasound and Ultrasound Therapy.

(TRUS) Transrectal sonography (also called transrectal ultrasonography, transrectal echography (TRE), endorectal ultrasound (ERUS or EUS)) is an ultrasound procedure used to examine the prostate gland, the rectum or bladder.
A small, lubricated transducer placed into the rectum releases sound waves, which create echoes as they enter the region of interest. A computer creates a picture called a sonogram.
TRUS is commonly used for guidance during a prostate needle biopsy and may be used to deliver brachytherapy and monitor cancer treatment. Transrectal ultrasonography detects enlargement, tumors and other abnormalities of the prostate, rectal polyps, rectal cancer, perianal infection, and sphincter muscle injuries. TRUS is also performed on male patients with infertility to view the prostate and surrounding structures and on patients with suspected bladder conditions or disease to view the bladder.

See also Transurethral Sonography, Endoscopic Ultrasound, Pelvic Ultrasound, Rectal Probe, Biplane Probe, Endocavitary Echography and High Intensity Focused Ultrasound.

Transurethral echography or sonography is used to detect small tumors of the urinary bladder or to visualize the urethra and surrounding muscles with special transducers. The bladder neck can be visualized using a transrectal probe.
In addition, high intensity focused ultrasound provides treatment of benign prostatic hyperplasia and adenocarcinoma of the prostate. Small catheter-based sectored tubular or planar transducers with highly directional energy deposition and rotational control are used for precise treatment. Regions of the prostate can be selective coagulatet while monitoring and controlling the treatment with MRI.

See also Urologic Ultrasound, Lithotripsy, Reflux Sonography, Ultrasound Therapy, Interventional Ultrasound and Thermotherapy.