Also called B-mode echography, B-mode sonography, 2D-mode, and sonogram.
B-mode ultrasound (Brightness-mode) is the display of a 2D-map of B-mode data, currently the most common form of ultrasound imaging.
The development from A-mode to B-mode is that the ultrasound signal is used to produce various points whose brightness depends on the amplitude instead of the spiking vertical movements in the A-mode. Sweeping a narrow ultrasound beam through the area being examined while transmitting pulses and detecting echoes along closely spaced scan lines produces B-scan images. The vertical position of each bright dot is determined by the time delay from pulse transmission to return of the echo, and the horizontal position by the location of the receiving transducer element.
To generate a rapid series of individual 2D images that show motion, the ultrasound beam is swept repeatedly. The returning sound pulses in B-mode have different shades of darkness depending on their intensities. The varying shades of gray reflect variations in the texture of internal organs. This form of display (solid areas appear white and fluid areas appear black) is also called gray scale.

Different types of displayed B-mode images are:
The probe movement can be performed manual (compound and static B-scanner) or automatic (real-time scanner).
The image reconstruction can be parallel or sector type.

See also B-Scan, 4B-Mode, and Harmonic B-Mode Imaging.

Ultrasound at the microbubble resonance frequency can cause bubble rupture at high acoustic power (mechanical index (MI) greater than 0.5). The result is a transient high-amplitude, broadband signal containing all frequencies, not only the harmonics. It will create a strong signal in B-mode or a short-lasting multicolored, mosaic-like effect in color Doppler sonography.
Several terms for this typical signal have been used, e.g. induced or stimulated acoustic emission, loss of correlation imaging and sono-scintigraphy.

[This entry is marked for removal.]

From POINT Biomedical Corp
CARDIOsphere® is an ultrasound contrast agent for assessment of myocardial perfusion in patients with coronary artery disease composed of highly echogenic bispheres.
PB127 is a new developed microbubble with a bilayer polymer/albumin shell filled with nitrogen gas that has ideal characteristics for power harmonic Doppler. They can be destroyed by high power ultrasound, and spectral decorrelation between ultrasound pulses is maximized by rapid dissolution of the released nitrogen gas.
POINT Biomedical Corp. announced (March 01, 2004) that it has completed two Phase 3 trials of CARDIOsphere®. The Phase 3 trials were designed to evaluate the performance of CARDIOsphere® imaging relative to radionuclide imaging for detecting obstructive coronary artery disease and identifying the anatomic location of perfusion defects.

(CEUS) Contrast agents increase the reflection of ultrasonic energy, improve the signal to noise ratio and caused by that the detection of abnormal microvascular and macrovascular disorders. Contrast enhanced ultrasound is used in abdominal ultrasound (liver sonography) as well as in cerebrovascular examinations e.g., for an accurate grading of carotid stenosis. The used contrast agents are safe and well tolerated.

The quality of the enhancement depends on:
The additional use of ultrasound contrast agents (USCAs) may overcome typical limitations like poor contrast of B-mode imaging or limited sensitivity of Doppler techniques. The development of new ultrasound applications (e.g., blood flow imaging, perfusion quantification) depends also from the development of pulse sequences for bubble specific imaging. In addition, contrast enhanced ultrasound improves the monitoring of ultrasound guided interventions like RF thermal ablation.

See also Contrast Enhanced Doppler Imaging, Contrast Harmonic Imaging, Contrast Imaging Techniques and Contrast Pulse Sequencing.

Many different contrast imaging techniques have been developed. Most are either variations, hybrids, or combinations of the following ultrasound techniques:

See also Coherent Contrast Imaging, Ultrasound Picture and Targeted Contrast Imaging.