Release burst imaging is a method based on the combination of multiple high frequency, broadband-detection pulses with a separate release burst. Release burst imaging is optimally suited to the characteristic of ultrasound contrast agents.
This method allows to improve both contrast sensitivity and imaging resolution. Imaging and transient enhanced scattering can be optimized separately. The release burst mode can be combined with a Doppler method to remove residual clutter signals from moving tissue.

See also Repetition Rate.

Selective detection of the microbubble contrast medium can be enhanced by Doppler processing that removes signals with zero Doppler frequency shifts. This will remove tissue harmonics. By detecting overlong bursts of inverted pulses and using Doppler detection methods, very high sensitivity to microbubbles can be achieved. The bubbles can be detected at sufficiently low incident power levels to avoid destroying them. Pulse inversion Doppler has demonstrated the first real-time images of myocardial perfusion using perfluorocarbon gas agents.

See also Pulse Inversion Imaging, Myocardial Contrast Echocardiography, and Perfluorochemicals.

Ultrasound technology with its advancements is vital for delivering high-quality patient care. Innovations including high-frequency ultrasound, 3D//4D imaging, contrast enhanced ultrasound, elastography, and point-of-care ultrasound, have expanded the capabilities of ultrasound imaging and improved diagnostic accuracy.
B-Mode imaging, also known as brightness mode, is the fundamental technique in ultrasound imaging. It produces two-dimensional images based on the echoes received from tissues and organs. Understanding the principles of B-Mode imaging, such as gain adjustment, depth control, and image optimization, is crucial for obtaining diagnostically valuable images. M-Mode imaging, on the other hand, allows for the visualization of motion over time, enabling assessment of cardiac structures and function, as well as fetal heart rate.
High-frequency ultrasound refers to the use of ultrasound waves with frequencies greater than 10 MHz. This technology enables improved resolution, allowing for detailed imaging of superficial structures like skin, tendons, and small organs. High-frequency ultrasound has found applications in dermatology, ophthalmology, and musculoskeletal imaging.
Traditional 2D ultrasound has been augmented by the advent of 3D ultrasound technology. By acquiring multiple 2D images from different angles, this technique construct a volumetric representation of the imaged area. The addition of 4D ultrasound in real-time motion adds further value by capturing dynamic processes.
Doppler imaging employs the Doppler effect to evaluate blood flow within vessels and assess hemodynamics. Color Doppler assigns color to different blood flow velocities, providing a visual representation of blood flow direction and speed. Spectral Doppler displays blood flow velocities as a waveform, allowing for detailed analysis of flow patterns, resistance, and stenosis.
Contrast enhanced ultrasound employs microbubble contrast agents to enhance the visualization of blood flow and tissue perfusion. By injecting these agents intravenously, sonographers can differentiate between vascular structures and lesions. Elastography is a technique that measures tissue elasticity or stiffness. It assists in differentiating between normal and abnormal tissues, aiding in the diagnosis of various conditions such as liver fibrosis, breast lesions, and thyroid nodules.
Fusion imaging combines ultrasound with other imaging modalities, such as computed tomography (CT), magnetic resonance imaging (MRI), or positron emission tomography (PET). By overlaying or merging ultrasound images with those obtained from other modalities, the user can precisely locate and characterize abnormalities, guide interventions, and improve diagnostic accuracy. Fusion imaging has proven particularly useful in areas such as interventional radiology, oncology, and urology.
See also Equipment Preparation, Environmental Protection, Handheld Ultrasound, Portable Ultrasound and Ultrasound Accessories and Supplies.

(AUS) Abdominal ultrasound, also known as abdominal sonography, is a medical imaging technique that focuses on the visualization and assessment of the abdominal organs. While 'abdominal ultrasound' is the commonly used term, there are alternative terms that can be used to refer to this imaging modality: (TAE) transabdominal echography, abdominal ultrasonography, sonogram, FAST (Focused Assessment with Sonography for Trauma).
Abdominal ultrasound imaging is an invaluable clinical tool for identifying the underlying cause of abdominal pain. An abdominal ultrasound examination encompasses a comprehensive evaluation of the liver, gallbladder, biliary tree, pancreas, spleen, kidneys, and abdominal blood vessels. It is a cost-effective, safe, and non-invasive medical imaging modality that is typically utilized as the initial diagnostic investigation.
Advanced ultrasound techniques, such as high-resolution ultrasound, endoscopic ultrasound, and contrast-enhanced Doppler, further enhance the detection of small lesions and provide detailed information for precise diagnosis.
To prepare for an abdominal ultrasound, it is recommended to have nothing to eat or drink for at least 8 hours, starting from midnight the night before the examination.

Indications:
FAST (Focused Assessment with Sonography for Trauma) is a rapid diagnostic test used for trauma patients. It sequentially evaluates the presence of free fluid in the pericardium (hemopericardium) and in four specific views of the abdomen. These views include the right upper quadrant (RUQ), left upper quadrant (LUQ), subcostal, and suprapubic views. They aid in identifying hemoperitoneum in patients with potential truncal injuries. The space between the liver and the right kidney (RUQ), known as Morison's pouch, is a location where intraperitoneal fluid can accumulate.
Emergency abdominal ultrasonography is indicated in cases of suspected aortic aneurysm, appendicitis, biliary and renal colic, as well as blunt or penetrating abdominal trauma. It plays a crucial role in the timely assessment and management of these conditions, providing critical information to guide appropriate treatment decisions.

See also Handheld Ultrasound, Pelvic Ultrasound, Pregnancy Ultrasound, Prostate Ultrasound, Interventional Ultrasound and Pediatric Ultrasound.

(UCA / USCA) Ultrasonography is the most commonly performed diagnostic imaging procedure. The introduction of sonographic contrast media into routine practice modifies the use of ultrasound in a variety of clinical applications. USCAs consist of microbubbles filled with air or gases and can be classified according to their pharmacokinetics. Among the blood pool agents, transpulmonary ultrasound contrast agents offer higher diagnostic potential compared to agents that cannot pass the pulmonary capillary bed after a peripheral intravenous injection. In addition to their vascular phase, some USCAs can exhibit a tissue- or organ-specific phase.
The sonogram image quality is improved either by decreasing the reflectivity of the undesired interfaces or by increasing the backscattered echoes from the desired regions.

Different types of ultrasound contrast agents:
Ultrasound contrast agents act as echo-enhancers, because of the high different acoustic impedance at the interface between gas and blood. The enhanced echo intensity is proportional to the change in acoustical impedance as the sound beam crosses from the blood to the gas in the bubbles.

The ideal qualities of an ultrasound contrast agent:
A typical ultrasound contrast agent consists of a thin flexible or rigid shell composed of albumin, lipid, or polymer confining a gas such as nitrogen, or a perfluorocarbon. The choice of the microbubble shell and gas has an important influence on the properties of the agent.
Current generations of microbubbles have a diameter from 1 μm to 5 μm. The success of these agents is mostly dependent on the small size and on the stability of their shell, which allows passage of the microbubbles through the pulmonary circulation. Microbubbles must be made smaller than the diameter of capillaries or they would embolize and be ineffective and perhaps even dangerous.
The reflectivity of these microbubbles is proportional to the fourth power of a particle diameter but also directly proportional to the concentration of the contrast agent particles themselves.
Ultrasound contrast agents produce unique acoustic signatures that allow to separate their signal from tissue echoes and to depict whether they are moving or stationary. This enables the detection of capillary flow and of targeted microbubbles that are retained in tissues such as normal liver.
The new generation of contrast media is characterized by prolonged persistence in the vascular bed which provides consistent enhancement of the arterial Doppler signal. Contrast agents make it also possible to perform dynamic and perfusion studies. Targeted contrast imaging agents are for example taken up by the phagocytic cell systems and thus have liver/spleen specific effects.

See also Ultrasound Contrast Agent Safety, Adverse Reaction, Tissue-Specific Ultrasound Contrast Agent, and Bubble Specific Imaging.